Major symptoms associated with hypersensitivity1

These symptoms:

  • May lead to misdiagnosis of hypersensitivity as respiratory disease (pneumonia, bronchitis, pharyngitis), or gastroenteritis.
  • Worsen with continued therapy and can be life-threatening.
  • Usually resolve upon discontinuation of abacavir.

Symptoms reported with a frequency ≥10% (n=1803)1

Hover over the symptoms bars for the exact figures.

Physical and laboratory findings1

Physical findings Possible laboratory abnormalities
Lymphadenopathy Haematological: lymphopaenia, leukopenia and thrombocytopaenia
Mucous membrane lesions
(pharyngitis, conjunctivitis)
Chest x-ray normal or diffuse bilateral or lobular infiltrates
  Elevated liver enzymes (AST/ALT)
  Increased serum creatinine and creatinine phosphokinase


  1. Hetherington et al. Clin Ther. 2001; 23: 1603-1614.*

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